Tuesday, October 16, 2007

The Alzheimer's Diabete's Connection

Discovery Supports Theory of Alzheimer's Disease as Form of Diabetes

(Physorg.com) Research in the last few years has raised the possibility that Alzheimer’s memory loss could be due to a third form of diabetes. Now scientists at Northwestern University have discovered why brain insulin signaling -- crucial for memory formation -- would stop working in Alzheimer’s disease. They have shown that a toxic protein found in the brains of individuals with Alzheimer’s removes insulin receptors from nerve cells, rendering those neurons insulin resistant. (The protein, known to attack memory-forming synapses, is called an ADDL for “amyloid ß-derived diffusible ligand.”) The new findings, published online by the FASEB Journal, could help researchers determine which aspects of existing drugs now used to treat diabetic patients may protect neurons from ADDLs and improve insulin signaling in individuals with Alzheimer’s. (The FASEB Journal is a publication of the Federation of American Societies for Experimental Biology.)
Dr. Zach's Comments:
  • Many experts in the health care industry have noticed similarities between the mental effects of diabetes and Alzheimer's, and now research is showing it too. In fact, diabetes and Alzheimer's aren't the only two chronic lifestyle diseases with links to blood insulin levels. Studies have also linked heart disease to insulin mismanagement as well.
  • Not only do these diseases have common ties with insulin, but they are also all diseases that can almost always be controlled and even more importantly PREVENTED through changes in lifestyle.
  • So, how do you prevent diseases such as diabetes, Alzheimer's, Heart Disease and Cancer? The Answer lies in providing your body sufficient amount the nutrients it needs (foods, exercise, normal nerve function, rest, & peace) and avoiding exposure to toxic substances and deficiencies (in our food, environment, activity levels, etc.)
  • Want to learn more? Look for upcoming lectures and workshops at area churches and community events given by Dr. McCabe.